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Preface

Obstetrics by Ten Teachers is the oldest and most respected English language textbook on the subject. As editors we fully appreciate the responsibility to ensure its continuing success.

The first edition was published as Midwifery by Ten Teachers in 1917, and was edited under the direction of Comyns Berkley (Obstetric and Gynaecological Surgeon to the Middlesex Hospital). The aims of the book as detailed in the preface to the first edition still pertain today:

This book is frankly written for students preparing for their final examination, and in the hope that it will prove useful to them afterwards, and to others who have passed beyond the stage of examination.

Thus, whilst the 19th edition is written for the medical student, we hope the text retains its usefulness for the trainee obstetrician and general pratitioners. The 19th edition continues the tradition, re-established with the 18th edition, of utilizing the collective efforts of ten teachers of repute. The ten teachers teach in medical schools that vary markedly in the philosophy and structure of their courses. Some adopt a wholly problem-based approach, while others adopt a more traditional ‘subject-based’ curriculum. All of the ten teachers have an active involvement in both undergraduate and postgraduate teaching, and all have previously written extensively within their areas of expertise. Some of the contributors, such as Gary Mires, have been at the forefront of innovations in undergraduate teaching, and have been heavily involved in developing the structure of courses and curricula. In contrast, other teachers are at earlier stages in their career: Clare Tower is a clinical lecturer, closely involved in the day-to-day tutoring of students. The extensive and diverse experience of our ten teachers should maximize the relevance of the text to today’s medical students.

This 19th edition has been extensively revised and in many places entirely rewritten but throughout the textbook we have endeavoured to continue the previous editors’ efforts to incorporate clinically relevant material.

Finally, we echo the previous editors in hoping that this book will enthuse a new generation of obstetricians to make pregnancy and childbirth an even safer and more fulfilling experience.

Philip N Baker

Louise C Kenny 2011

Commonly used abbreviations

 

 

 

 

 

 

 

 

 

 

2,3-DPG

2,3-diphosphoglycerate

 

3D

three-dimensional

 

AC

abdominal circumference

 

aCL

anti-cardiolipin antibodies

 

ACR

American College of Rheumatology

 

ACTH

adrenocorticotrophic hormone

 

AFI

amniotic fluid index

 

AIDS

acquired immunodeficiency syndrome

 

AP

anteroposterior

 

APH

antepartum haemorrhage

 

APS

antiphospholipid syndrome

 

ARM

artificial rupture of membranes

 

ASBAH

Association for spina bifida and hydrocephalus

 

BMI

body mass index

 

BMR

basal metabolic rate

 

BPD

biparietal diameter

 

bpm

beats per minute

 

BPP

biophysical profile

 

BV

bacterial vaginosis

 

CBG

cortisol-binding globulin

 

CDC

Communicable Disease Center

 

CEMACH

Confidential Enquiry into Maternal and Child Health

 

CEMD

Confidential Enquiries into Maternal Death

 

CF

cystic fibrosis

 

CKD

chronic kidney disease

 

CMACE

Centre for Maternal and Child Enquiries

 

CMV

cytomegalovirus

 

CNST

Clinical Negligence Scheme for Trusts

 

CPD

cephalopelvic disproportion

 

CPR

cardiopulmonary resuscitation

 

CRH

corticotrophin-releasing hormone

 

CRL

crown–rump length

 

CRM

clinical risk management

 

CSE

combined spinal–epidural

 

CT

computed tomography

 

CTG

cardiotocograph

 

CTPA

computed tomography pulmonary angiogram

 

CVS

chorion villus sampling

 

DCDA

dichorionic diamniotic

 

DDH

developmental dysplasia of the hip

 

DHA

docosahexaenoic acid

 

DHEA

dihydroepiandrosterone

 

DIC

disseminated intravascular coagulation

 

DVT

deep vein thrombosis

 

 

 

 

xii

Commonly used abbreviations

 

eAg

e antigen

 

ECG

electrocardiogram

 

ECT

electroconvulsive therapy

 

ECV

external cephalic version

 

EDD

estimated date of delivery

 

EEG

electroencephalography

 

EFM

external fetal monitoring

 

EFW

estimate of fetal weight

 

EIA

enzyme immunoassay

 

ERCS

elective repeat Caesarean section

 

FBS

fetal scalp blood sampling

 

FEV1

forced expiratory volume in 1 second

 

fFN

fetal fibronectin

 

FGR

fetal growth restriction

 

FHR

fetal heart rate

 

FL

femur length

 

FRC

functional residual capacity

 

fT4

free T4

 

FVS

fetal varicella syndrome

 

G6PD

glucose 6-phosphate dehydrogenase

 

GBS

group B streptococcus

 

GDM

gestational diabetes mellitus

 

GFR

glomerular filtration rate

 

GMH-IVH

germinal matrix-intraventricular haemorrhage

 

GnRH

gonadotrophin releasing hormone

 

GP

general practitioner

 

HAART

highly active antiretroviral therapy

 

HbF

fetal haemoglobin

 

HBIG

hepatitis B immunoglobulin

 

HBsAG

hepatitis B surface antigen

 

HBV

hepatitis B virus

 

HC

head circumference

 

hCG

human chorionic gonadotrophin

 

HCV

hepatitis C virus

 

HDFN

haemolytic disease of the fetus and newborn

 

HELLP

haemolysis, elevation of liver enzymes and low platelets

 

hGH

human growth hormone

 

HIE

hypoxic–ischaemic encephalopathy

 

HIV

human immunodeficiency virus

 

hPL

human placental lactogen

 

HSV

herpes simplex virus

 

IBD

inflammatory bowel disease

 

IDDM

insulin-dependent diabetes mellitus

 

Ig

immunoglobulin

 

IGF

insulin-like growth factor

 

IgG

immunoglobulin G

 

INR

international normalized ratio

 

IOL

induction of labour

 

IRT

immunoreactive trypsin

 

 

 

 

Commonly used abbreviations

xiii

ITP

thrombocytopenic purpura

 

IU

international units

 

IUGR

intrauterine growth restriction

 

IVC

inferior vena cava

 

IVF

in vitro fertilization

 

LA

lupus anticoagulant

 

LDH

lactate dehydrogenase

 

LIF

leukaemia inhibitory factor

 

LLETZ

large loop excision of the transformation zone

 

LMP

last menstrual period

 

LMWH

low molecular weight heparin

 

MAS

meconium aspiration syndrome

 

MCA

middle cerebral artery

 

MCADD

medium chain acyl coenzyme A dehydrogenase

 

MCDA

monochorionic diamniotic

 

MCMA

monochorionic monoamniotic

 

MI

myocardial infarction

 

MMR

maternal mortality ratio; measles, mumps and rubella vaccine

 

MRI

magnetic resonance imaging

 

MSLC

Maternity Services Liaison Committee

 

MSU

midstream specimen of urine

 

NCT

National Childbirth Trust

 

NHS

National Health Service

 

NHSLA

NHS Litigation Authority

 

NICE

National Institute for Health and Clinical Excellence

 

NIDDM

non-insulin-dependent diabetes mellitus

 

NIPE

newborn and infant physical examination

 

NK

natural killer

 

NO

nitrous oxide

 

NYHA

New York Heart Association

 

OGTT

oral glucose tolerance test

 

PAI

plasma activator inhibitor

 

PAPP-A

pregnancy associated plasma protein-A

 

PBC

primary biliary cirrhosis

 

PCA

patient-controlled analgesia

 

pCO2

partial pressure of carbon dioxide

 

PCR

polymerase chain reaction

 

PE

pulmonary embolism

 

PEP

polymorphic eruption of pregnancy

 

PG

pemphigoid gestationis

 

PH

pulmonary hypertension

 

pO2

partial pressure of oxygen

 

PPH

postpartum haemorrhage

 

PPHN

persistent pulmonary hypertension of the newborn

 

PPROM

preterm prelabour rupture of membranes

 

PT

prothrombin time

 

PTCA

percutaneous transluminal coronary angioplasty

 

PTH

parathyroid hormone

 

PTL

preterm labour

 

 

 

 

xiv

Commonly used abbreviations

 

PTU

propylthiouracil

 

PVL

periventricular leukomalacia

 

RA

rheumatoid arthritis

 

RCOG

Royal College of Obstetricians and Gynaecologists

 

RDS

respiratory distress syndrome

 

REM

rapid eye movement

 

SANDS

Stillbirth and Neonatal Death Society

 

SARS

severe acute respiratory syndrome

 

SCD

sickle cell disease

 

SFH

symphysis–fundal height

 

SGA

small for gestational age

 

SLE

systemic lupus erythematosus

 

SROM

spontaneous rupture of the membranes

 

SSRI

selective serotonin reuptake inhibitors

 

T3

tri-iodothyronine

 

T4

thyroxine

 

TAMBA

Twins and Multiple Birth Association

 

TCA

tricyclic antidepressant drugs

 

TENS

transcutaneous electrical nerve stimulation

 

TOF

tracheo-oesophageal fistula

 

tPA

tissue plasminogen activator

 

TPHA

T. pallidum haemagglutination assay

 

TRH

thyrotrophin releasing hormone

 

TSH

thyroid stimulating hormone

 

TTN

transient tachypnoea of the newborn

 

TTTS

twin-to-twin transfusion syndrome

 

UFH

unfractionated heparin

 

UTI

urinary tract infection

 

VACTERL

Vertebral, Anal, Cardiac, Tracheal, (O)Esophageal, Renal and Limb

 

VBAC

vaginal birth after Caesarean

 

VDRL

Venereal Diseases Research Laboratory

 

VKDB

vitamin K deficiency bleeding

 

VTE

venous thromboembolic disease

 

VWF

von Willebrand factor

 

VZIG

varicella zoster immunoglobulin

 

VZV

varicella zoster virus

 

WHO

World Heath Organization

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

C H A P T E R 1

O B S T E T R I C H I S T O R Y T A K I N G

 

 

 

 

 

A N D E X A M I N A T I O N

 

 

 

 

 

Lucy Kean

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Etiquette in taking a history....................................................................

1

Examination ......................................................................................................

6

 

 

Where to begin................................................................................................

1

General medical examination................................................................

7

 

 

Dating the pregnancy .................................................................................

1

Presentation skills......................................................................................

11

 

 

Taking the history .........................................................................................

2

History template..........................................................................................

12

 

 

Identifying risk.................................................................................................

6

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

O V E R V I E W

Taking a history and performing an obstetric examination are quite different from their medical and surgical equivalents. Not only will the type of questions change with gestation but also will the purpose of the examination. The history will often cover physiology, pathology and psychology and must always be sought with care and sensitivity.

Etiquette in taking a history

Patients expect doctors and students to be well presented and appearances do have an enormous impact on patients, so make sure that your appearance is suitable before you enter the room.

When meeting a patient for the first time, always introduce yourself; tell the patient who you are and say why you have come to see them. If you are a medical student, some patients will decide that they do not wish to talk to you. This may be for many reasons and, if your involvement in their care is declined, accept without questioning.

Some areas of the obstetric history cover subjects that are intensely private. In occasional cases there may be events recorded in the notes that are not known by other family members, such as previous terminations of pregnancy. It is vital that the history taker is sensitive to each individual situation and does not simply follow a formula to get all the facts right.

Some women will wish another person to be present if the doctor or student is male, even just to take a history, and this wish should be respected.

Where to begin

The amount of detail required must be tailored to the purpose of the visit. At a booking visit, the history must be thorough and meticulously recorded. Once

this baseline information is established, many women find it tedious to go over all this information again. Before starting, ask yourself what you need to achieve. In late pregnancy, women will be attending the antenatal clinic for a particular reason. It is certainly acceptable to ask why the patient has attended in the opening discussion. For some women it will be a routine visit (usually performed by the midwife or general practitioner), others are attending because there is or has been a problem.

Make sure that the patient is comfortable (usually seated but occasionally sitting on a bed).

It is important to establish some very general facts when taking a history. Asking for the patient’s age or date of birth and whether this is a first pregnancy are usually safe opening questions.

At this stage you can also establish whether a woman is working and, if so, what she does.

Dating the pregnancy

Pregnancy has been historically dated from the last menstrual period (LMP), not the date of conception. The median duration of pregnancy is 280 days (40 weeks) and this gives the estimated date of delivery (EDD). This assumes that:

the cycle length is 28 days;

ovulation occurs generally on the 14th day of the cycle;

2Obstetric history taking and examination

the cycle was a normal cycle (i.e. not straight after stopping the oral contraceptive pill or soon after a

previous pregnancy).

The EDD is calculated by taking the date of the LMP, counting forward by nine months and adding 7 days. If the cycle is longer than 28 days, add the difference between the cycle length and 28 to compensate.

In most antenatal clinics, there are pregnancy calculators (wheels) that do this for you (Figure 1.1). It is worth noting that pregnancy-calculating wheels do differ a little and may give dates that are a day or two different from those previously calculated. While this should not make much difference, it is an area that often causes heated discussion in the antenatal clinic. Term is actually defined as 37–42 weeks and so the estimated time of delivery should ideally be defined as a range of dates rather than a fixed date, but women have been highly resistant to this idea and generally do want a specific date.

Almost all women who undergo antenatal care in the UK will have an ultrasound scan in the late first trimester or early second trimester. The purposes of this scan are to establish dates, to ensure that the pregnancy is ongoing and to determine the number of fetuses. If performed before 20 weeks, the ultrasound scan can be used for dating the pregnancy. After this time, the variability in growth rates of different fetuses makes it

Figure 1.1 Gestation calculator

unsuitable for use in defining dates. It has been shown that ultrasound-defined dates are more accurate than those based on a certain LMP and reduce the need for post-dates induction of labour. This may be because the actual time of ovulation in any cycle is much less fixed than was previously thought. Therefore, the UK National Screening Committee has recommended that pregnancy dates are set only by ultrasound. The crown–rump length is used up until 13 weeks 6 days, and the head circumference from 14 to 20 weeks. Regardless of the date of the LMP this EDD is used. It is important that an accurate EDD is established as a difference of a day or two can make a difference in the risk for conditions such as Down’s syndrome on serum screening. In addition, accurate dating reduces the need for post-dates induction of labour.

In late pregnancy, many women will have long forgotten their LMP date, but will know exactly when their EDD is, and it is therefore more straightforward to ask this.

Taking the history

Social history

Some aspects of history taking require considerable sensitivity, and the social history is one such area. There are important facts to establish, but in many cases these can come out at various different parts of the history and some can almost be part of normal conversation. It is important to have a list of things to establish in your mind. It is here more than anywhere that some local knowledge is helpful, as much can be gained from knowing where the patient lives. However, be careful not to jump to conclusions, as these can often be wrong.

The following facts demonstrate why a social history is important:

Women whose partners were unemployed or working in an unclassifiable role had a maternal

mortality rate seven times higher than women whose partners were employed according to the Confidential Enquiry into Maternal and Child Health 2003–2005 (CEMACH).

Social exclusion was seen in 18 out of 19 deaths

in women under 20 in the 1997–1999 Confidential Enquiries into Maternal Death (CEMD) (one

homeless teenager froze to death in a front garden).

Married women are more likely to request amniocentesis after a high-risk Down’s syndrome

screening result than unmarried women. Husbands clearly have a strong voice in decision making.

If a woman is unmarried, her partner cannot provide consent for a post-mortem after

stillbirth.

Domestic violence was reported in 12 per cent of the 378 women whose deaths were reported in

1997–1999.

Enquiry about domestic violence is extremely difficult. It is recommended that all women are seen on their own at least once during pregnancy, so that they can discuss this, if needed, away from an abusive partner. This is not always easy to accomplish. If you happen to be the person with whom this information is shared, you must ensure that it is passed on to the relevant team, as this may be the only opportunity the woman has to disclose it. Sometimes younger women find medical students and young doctors much easier to talk to. Be aware of this.

Smoking, alcohol and illicit drug intake also form part of the social history. Smoking causes a reduction in birthweight in a dose-dependent way. It also increases the risk of miscarriage, stillbirth and neonatal death. There are interventions that can be offered to women who are still smoking in pregnancy (see Chapter 8, Antenatal obstetric complications).

Complete abstinence from alcohol is advised, as the safety of alcohol is not proven. However, alcohol is probably not harmful in small amounts (less than one drink per day). Binge drinking is particularly harmful and can lead to a constellation of features in the baby known as fetal alcohol syndrome (see Chapter 8, Antenatal obstetric complications).

Enquiry about illicit drug taking is more difficult. Approximately 0.5–1 per cent of women continue to take illicit drugs during pregnancy. Be careful not to make assumptions. During the booking visit, the midwife should directly enquire about drug taking. If it is seen as part of the long list of routine questions asked at this visit, it is perceived as less threatening. However, sometimes this information comes to light at other times. Cocaine and crack cocaine are the most harmful of the illicit drugs taken, but all

Taking the history

3

have some effects on the pregnancy, and all have financial implications (see Chapter 8, Antenatal obstetric complications).

By the time you have finished your history and examination you should know the following facts that are important in the social history:

whether the patient is married or single and what sort of support she has at home (remember that

married women whose only support is a working husband may be very isolated after the birth of a baby);

generally whether there is a stable income coming into the house;

what sort of housing the patient occupies (e.g. a flat with lots of stairs and no lift may be

problematic);

whether the woman works and for how long she is planning to work during the pregnancy;

whether the woman smokes/drinks or uses drugs;

if there are any other features that may be important.

Previous obstetric history

Past obstetric history is one of the most important areas for establishing risk in the current pregnancy. It is helpful to list the pregnancies in date order and to discover what the outcome was in each pregnancy.

The features that are likely to have impact on future pregnancies include:

recurrent miscarriage (increased risk of miscarriage, fetal growth restriction (FGR));

preterm delivery (increased risk of preterm delivery);

early-onset pre-eclampsia (increased risk of pre-eclampsia/FGR);

abruption (increased risk of recurrence);

congenital abnormality (recurrence risk depends on type of abnormality);

macrosomic baby (may be related to gestational diabetes);

FGR (increased recurrence);

unexplained stillbirth (increased risk of gestational diabetes).

4Obstetric history taking and examination

The method of delivery for any previous births must be recorded, as this can have implications for planning in the current pregnancy, particularly if there has been a previous Caesarean section, difficult vaginal delivery, postpartum haemorrhage or significant perineal trauma.

When you have noted all the pregnancies, you can convert this into the obstetric shorthand of parity. This is often confusing. Remember that:

gravida is the total number of pregnancies regardless of how they ended;

parity is the number of live births at any gestation or stillbirths after 24 weeks.

In terms of parity, therefore, twins count as two. Thus a woman at 12 weeks in this pregnancy who has never had a pregnancy before is gravida 1, parity 0. If she delivers twins and comes back next time at 12 weeks, she will be gravida 2, parity 2 (twins). A woman who has had six miscarriages and is pregnant again with only one live baby born at 25 weeks will be gravida 8, parity 1.

The other shorthand you may see is where parity is denoted with the number of pregnancies that did not result in live birth or stillbirth after 24 weeks as a superscript number. The above cases would thus be defined as: para 00, para 20 (twins), para 16.

However, when presenting a history, it is much easier to describe exactly what has happened, e.g. ‘Mrs Jones is in her eighth pregnancy. She has had six miscarriages at gestations of 8–12 weeks and one spontaneous delivery of a live baby boy at 25 weeks. Baby Tom is now 2 years old and healthy’.

Past gynaecological history

The regularity of periods used to be important in dating pregnancy (see Dating the pregnancy p. 1). Women with very long cycles may have a condition known as polycystic ovarian syndrome. This is a complex endocrine condition and its relevance here is that some women with this condition have increased insulin resistance and a higher risk for the development of gestational diabetes.

Contraceptive history can be relevant if conception has occurred soon after stopping the combined oral contraceptive pill or depot progesterone preparations, as again, this makes dating by LMP more difficult. Also, some women will conceive with an intrauterine device still in situ. This carries an increase in the risk of miscarriage.

Previous episodes of pelvic inflammatory disease increase the risk for ectopic pregnancy. This is only of relevance in early pregnancy. However, it is important to establish that any infections have been adequately treated and that the partner was also treated.

The date of the last cervical smear should be noted. Every year a small number of women are diagnosed as having cervical cancer in pregnancy, and it is recognized that late diagnosis is more common around the time of pregnancy because smears are deferred. If a smear is due, it can be taken in the first trimester. It is important to record that the woman is pregnant, as the cells can be difficult to assess without this knowledge. It is also important that smears are not deferred in women who are at increased risk of cervical disease (e.g. previous cervical smear abnormality or very overdue smear). Gently taking a smear in the first trimester does not cause miscarriage and women should be reassured about this. Remember that if it is deferred at this point, it may be nearly a year before the opportunity arises again. If there has been irregular bleeding, the cervix should at least be examined to ensure that there are no obvious lesions present.

If a woman has undergone treatment for cervical changes, this should be noted. Knife cone biopsy is associated with an increased risk for both cervical incompetence (weakness) and stenosis (leading to preterm delivery and dystocia in labour, respectively). There is probably a very small increase in the risk of preterm birth associated with large loop excision of the transformation zone (LLETZ); however, women who have needed more than one excision are likely to have a much shorter cervix, which does increase the risk for second and early third trimester delivery.

Previous ectopic pregnancy increases the risk of recurrence to 1 in 10. It is also important to know the site of the ectopic and how it was managed. The implications of a straightforward salpingectomy for an ampullary ectopic are much less than those after a complex operation for a cornual ectopic. Women who have had an ectopic pregnancy should be offered an early ultrasound scan to establish the site of any future pregnancies.

Recurrent miscarriage may be associated with a number of problems. Antiphospholipid syndrome increases the risk of further pregnancy loss, FGR and pre-eclampsia. Balanced translocations can occasionally lead to congenital abnormality, and cervical incompetence can predispose to late second and early third trimester delivery. Also, women need

a great deal of support during pregnancy if they have experienced recurrent pregnancy losses.

Multiple previous first trimester terminations of pregnancy potentially increase the risk of preterm delivery, possibly secondary to cervical weakness. Sometimes information regarding these must be sensitively recorded. Some women do not wish this to be recorded in their hand-held notes.

Previous gynaecological surgery is important, especially if it involved the uterus, as this can have potential sequelae for delivery. In addition, the presence of pelvic masses such as ovarian cysts and fibroids should be noted. These may impact on delivery and may also pose some problems during pregnancy. A previous history of sub-fertility is also important. Four deaths occurred in CEMACH 2003–2005 of women with ovarian hyperstimulation syndrome following IVF. Donor egg or sperm use is associated with an increased risk of pre-eclampsia. The rate of preterm delivery is higher in assisted conception pregnancies, even after the higher rate of multiple pregnancies has been taken into account. Women who have undergone fertility treatment are often older and generally need increased psychological support during pregnancy.

Legally, you should not write down in notes that a pregnancy is conceived by IVF or donor egg or sperm unless you have written permission from the patient. It is obviously a difficult area, as there is an increased risk of problems to the mother in these pregnancies and therefore the knowledge is important. Generally, if the patient has told you herself that the pregnancy was an assisted conception, it is reasonable to state that in your presentation.

Taking the history

5

Major pre-existing diseases that impact on

pregnancy

Diabetes mellitus: macrosomia, FGR, congenital abnormality, pre-eclampsia, stillbirth, neonatal hypoglycaemia.

Hypertension: pre-eclampsia.

Renal disease: worsening renal disease, pre-eclampsia, FGR, preterm delivery.

Epilepsy: increased fit frequency, congenital abnormality.

Venous thromboembolic disease: increased risk during pregnancy; if associated thrombophilia, increased risk of thromboembolism and possible increased risk of pre-eclampsia, FGR.

Human immunodeficiency virus (HIV) infection: risk of mother-to-child transfer if untreated.

Connective tissue diseases, e.g. systemic lupus erythematosus: pre-eclampsia, FGR.

Myasthenia gravis/myotonic dystrophy: fetal neurological effects and increased maternal muscular fatigue in labour.

care received and clinical presentation, and should be made in a systematic and sensitive way at the antenatal booking visit. A good question to lead into this is ‘Have you ever suffered with your nerves?’. If women have had children before, you can ask whether they had problems with depression or ‘the blues’ after the births of any of them. Women with significant psychiatric problems should be cared for by a multidisciplinary team, including the midwife, GP, hospital consultant and psychiatric team.

Medical and surgical history

All pre-existing medical disease should be carefully noted and any associated drug history also recorded. The major pre-existing diseases that impact on pregnancy and their potential effects are shown in the box (also see Chapter 12, Medical diseases complicating pregnancy).

Previous surgery should be noted. Occasionally surgery has been performed for conditions that may continue to be a problem during pregnancy, such as Crohn’s disease. Rarely, complications from previous surgery, such as adhesional obstruction, present in pregnancy.

Psychiatric history is important to record. These enquiries should include the severity of the illness,

Drug history

It is vital to establish what drugs women have been taking for their condition and for what duration. You should also ask about over-the-counter medication and homeopathic/herbal remedies. In some cases, medication needs to be changed in pregnancy. For some women it may be possible to stop their medication completely for some or all of the pregnancy (e.g. mild hypertension). Some women need to know that they must continue their medication (e.g. epilepsy, for which women often reduce their medication for fear of potential fetal effects, with detriment to their own health).

Very few drugs that women of childbearing age take are potentially seriously harmful, but a few are,

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