- •Contributors of Campbell-Walsh-Wein, 12th Edition
- •Patient history and physical examination
- •Clinic visit set-up
- •Patient history
- •Chief complaint (CC)
- •History of present illness (HPI)
- •Constitutional symptoms.
- •Pain.
- •Hematuria.
- •Lower urinary tract symptoms (LUTS).
- •Urinary incontinence
- •Erectile dysfunction (ED).
- •Other urologic conditions.
- •Past medical/surgical history
- •Performance status
- •Medications
- •Social history
- •Family history
- •Review of systems
- •Physical examination
- •Vital signs
- •General appearance
- •Kidneys
- •Bladder
- •Penis
- •Scrotum and contents
- •Digital rectal examination (DRE)
- •Pelvic examination in the female
- •Laboratory tests
- •Urinalysis
- •UA evaluation
- •Specific gravity and osmolality.
- •Blood/hematuria.
- •Leukocyte esterase (LE) and nitrite.
- •Bacteria.
- •Yeast.
- •Urine cytology
- •Serum studies
- •Creatinine and glomerular filtration rate (GFR)
- •Prostate-specific antigen (PSA)
- •Alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), and lactate dehydrogenase (LDH)
- •Endocrinologic studies
- •Parathyroid hormone
- •Office diagnostic procedures
- •Uroflowmetry
- •Post void residual (PVR)
- •Cystometography and urodynamic studies
- •Cystourethroscopy
- •Imaging of the urinary tract
- •Plain abdominal radiography.
- •Retrograde pyelogram (RPG).
- •Loopography.
- •Retrograde urethrography.
- •Voiding cystourethrogram (VCUG).
- •Functional imaging with nuclear scintigraphy
- •Technetium 99m –diethylenetriamine pentaacetic acid (99m TC-DTPA)
- •Technetium 99m –dimercaptosuccinic acid (99m TC-DMSA)
- •Technetium 99m -mercaptoacetyltriglycine (99m TC-MAG3)
- •Diuretic scintigraphy
- •Phamacokinetics.
- •Phases of dynamic renal imaging.
- •Urologic ultrasonography
- •Renal ultrasonography.
- •Bladder ultrasonography.
- •Scrotal ultrasonography.
- •Ultrasonography of the penis and male urethra.
- •Transperineal/translabial ultrasound.
- •Transrectal ultrasonography of the prostate (TRUS).
- •Urologic computed tomography (CT)
- •Types of CT.
- •Urolithiasis.
- •Cystic and solid renal masses.
- •Urologic magnetic resonance imaging (MRI)
- •Adrenal MRI.
- •Renal MRI.
- •Urothelial cell carcinoma (upper and lower tract).
- •Prostate MRI.
- •Nuclear medicine in urology
- •Positron emission tomography (PET).
- •Hematuria
- •Causes of microscopic hematuria
- •Selecting patients for evaluation
- •Lower tract evaluation
- •Upper tract evaluation
- •Suggested readings
16 CHAPTER 1 Evaluation of the Urologic Patient
Parathyroid Hormone
Ordered for patients with hypercalcemia and calcium-based nephrolithiasis.
OFFICE DIAGNOSTIC PROCEDURES
Uroflowmetry
Used to assess voiding pattern including workup of suspected bladder outlet obstruction. Information obtained includes flow rates, voided volume, and voiding curve/pattern.
Post Void Residual (PVR)
The PVR is the volume of residual urine in the bladder measured via bladder scan (may be inaccurate in patients with obesity or ascites) or catheterization following voiding. Acceptable volumes are patient dependent; however, volumes ,100 cc are generally considered within acceptable range.
Cystometography and Urodynamic Studies
Components of urodynamic studies include cystometrography, electromyography, urethral pressure profile, and pressure flow studies. This study is used for patients requiring a comprehensive workup of urinary storage and evacuation.
Cystourethroscopy
This procedure allows for direct visualization and evaluation of the lower urinary tract using a flexible cystoscope.
Imaging of the Urinary Tract
Imaging plays a critical role in the diagnosis and management of urologic disease.
Plain Abdominal Radiography. Conventional radiography study intended to display the kidneys, ureters, and bladder (KUB). Indi- cations for obtaining a plain film include scout film, assessment of residual contrast from previous imaging procedure, preand posttreatment assessment of renal calculus disease, assessment of the position of drains and stents (Fig. 1.3), and/or adjunct to the investigation of blunt or penetrating trauma to the urinary tract.
Retrograde Pyelogram (RPG). The RPG allows for opacification of the ureters and intrarenal collecting system via retrograde injection of contrast media (Fig. 1.4). Cystoscopy is performed, and a
CHAPTER 1 Evaluation of the Urologic Patient 17
FIG. 1.3 KUB demonstrating residual stone fragments (arrows) adjacent to a right ureteral stent 1 week after right extracorporeal shock wave lithotripsy.
Right #2
Right
A B
FIG. 1.4 (A) Right retrograde pyelogram performed using an 8-Fr cone-tipped ureteral catheter and dilute contrast material. The ureter and intrarenal collecting system are normal. (B) Left retrograde pyelogram using an 8-Fr cone-tipped ureteral catheter. A filling defect in the left distal ureter (arrow) is a low-grade transitional cell carcinoma. The ureter demonstrates dilation, elongation, and tortuosity, the hallmarks of chronic obstruction.
18 CHAPTER 1 Evaluation of the Urologic Patient
ureteral catheter is used to intubate the desired ureteral orifice. Contrast is injected, and fluoroscopic images are obtained. Indicated to evaluate congenital or acquired ureteral obstruc- tion, elucidation of filling defects and deformities of the ureters or intrarenal collecting systems, opacification or distention of col- lecting system to facilitate percutaneous access, and evaluation of hematuria, in conjunction with ureteroscopy or stent placement, surveillance of transitional cell carcinoma, and/or evaluation of traumatic or iatrogenic injury to the ureter or collecting system. Loopography. This is a diagnostic procedure performed in patients having undergone previous urinary diversion (Fig. 1.5). A loopogram
A B
Postdrain
C
FIG. 1.5 Loopogram in a patient with epispadius/exstrophy and ileal conduit urinary diversion. (A) Plain film prior to contrast administration. (B) After contrast administration via a catheter placed in the ileal conduit, free reflux of both ureterointestinal anastomoses is demonstrated. (C) A postdrain radiograph demonstrates persistent dilation of the proximal loop indicating mechanical obstruction of the conduit (arrows).
CHAPTER 1 Evaluation of the Urologic Patient 19
performed on an ileal conduit diversion will allow visualization of the ureters and upper collecting systems due to freely refluxing ureterointestinal anastomoses. A small-gauge catheter is inserted via the ostomy and contrast is gently introduced. Plain or fluoro- scopic images are obtained. Indications include evaluation of infection, hematuria, renal insufficiency or pain following urinary diversion, surveillance of upper urinary tract for obstruction of urothelial neoplasia and/or evaluation of the integrity of the intestinal segment or reservoir.
Retrograde Urethrography. This is a study to evaluate the anterior and posterior urethra (Fig. 1.6). The patient is positioned obliquely to allow for evaluation of the full length of the urethra. The penis is placed on slight stretch, and contrast is introduced via a catheter inserted into the fossa navicularis. Indications include identifying location and length of urethral stricture, assessment of foreign bodies, evaluation of penile or urethral penetrating trauma, and/ or evaluation of traumatic gross hematuria.
Voiding Cystourethrogram (VCUG). This is an imaging study used to the evaluate the anatomy of the bladder and urethra (Fig. 1.7) as
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Balloon |
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Normal RUG using |
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catheter technique |
B |
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Bladder |
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Prostatic |
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Membranous |
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Penile |
Normal “cone” |
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urethra |
of bulbar urethra |
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C |
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Bulbar urethra |
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Normal retrograde urethrogram |
FIG. 1.6 Normal retrograde urethrogram demonstrating (A) the balloon technique for retrograde urethrography, (B) Brodney clamp (arrowhead) technique; note the bulbar urethral stricture (arrow), and (C) normal structures of the male urethra.